主要自发性肺胸部的门诊治疗:一个开放的随机对照试验
Rob J Hallifax1, Edward McKeown2, Parthipan Sivakumar3
1Oxford Centre for Respiratory Medicine, University of Oxford, Oxford, UK.
Lancet (London, England)
|July 6, 2020
概括
主要自发性肺胸病 (PSP) 的门诊治疗显著缩短了住院时间. 然而,与标准治疗相比,这种方法导致不良事件的发生率更高.
科学领域:
- 胸部手术
- 肺病学
- 医疗器械
背景情况:
- 主要自发性肺胸炎 (PSP) 影响年轻,健康的人.
- 目前的治疗策略往往导致长期住院.
- 对于PSP的门诊选择的疗效和安全性存在有限的数据.
研究的目的:
- 为了比较PSP患者的门诊治疗和标准治疗的住院时间.
- 评估PSP的门诊治疗的安全性.
主要方法:
- 在英国24家医院进行的开放性随机对照试验,涉及236名患有症状的PSP的成年人 (16至55岁).
- 患者被随机分为出院器械或基于标准指南的治疗 (吸气,胸管插入或两者兼而有之).
- 主要结论是住院时间的总长度,包括在30天内重新入院.
主要成果:
- 与标准治疗相比,门诊治疗的平均住院时间显著缩短 (0 天); p< 0. 0001).
- 47%的患者出现了不良事件,在门诊组中为55%,在标准治疗组中为39%.
- 所有14个严重不良事件都发生在门诊组中,其中8个与干预有关.
结论:
- 对PSP的门诊治疗显著减少了住院时间和30天内重新入院的时间.
- 这种方法与不良事件的风险增加有关.
- 在需要干预的门诊患者中,门诊设备可能适合治疗PSP.
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