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相关概念视频

Responses to Heat and Cold Stress02:45

Responses to Heat and Cold Stress

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Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
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Factors Influencing Microbial Growth: Temperature01:27

Factors Influencing Microbial Growth: Temperature

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Microorganisms display remarkable adaptations, enabling them to thrive in diverse ecological niches across a wide range of temperatures. Temperature profoundly influences microbial growth by affecting enzymatic activity, membrane fluidity, and other cellular processes.Each microorganism operates within a specific temperature range defined by three cardinal points: minimum, optimum, and maximum. Below the minimum temperature, membranes lose fluidity, halting transport processes. Above the...
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Thermosensation01:43

Thermosensation

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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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Temperature Dependent Deformation01:12

Temperature Dependent Deformation

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In a nonhomogeneous rod made up of steel and brass, restrained at both ends and subjected to a temperature change, several steps are involved in calculating the stress and compressive load. Due to the problem's static indeterminacy, one end support is disconnected, allowing the rod to experience the temperature change freely. Next, an unknown force is applied at the free end, triggering deformations in the rod's steel and brass portions. These deformations are then calculated and added...
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Thermoregulation01:26

Thermoregulation

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The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
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Physical Methods for Controlling Microbial Growth: Temperature01:23

Physical Methods for Controlling Microbial Growth: Temperature

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Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...
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相关实验视频

Updated: Dec 14, 2025

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
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温度依赖的生长有助于长期感应寒冷

Yusheng Zhao1, Rea L Antoniou-Kourounioti1, Grant Calder1,2

  • 1John Innes Centre, Norwich Research Park, Norwich, UK.

Nature
|July 17, 2020
PubMed
概括

植物使用缓慢的NTL8蛋白积累,由温度依赖的生长驱动,以感知冬季的进展,并调节VIN3,使季节性发展.

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A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
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科学领域:

  • 植物生物学
  • 分子生物学
  • 表观遗传学

背景情况:

  • 温度对于生物的生长和季节性发展至关重要.
  • 植物必须理解长期的温度变化,
  • 在植物中整合长期温度暴露的机制在很大程度上是未知的.

研究的目的:

  • 研究植物长期温度感应的分子机制.
  • 确定控制VERNALIZATION INSENSITIVE 3 (VIN3) 缓慢的季节性上调的因素
  • 阐明植物如何解释冬季进展的发展时间.

主要方法:

  • 转发基因查以确定影响VIN3调节的突变.
  • 对转录因子NTL8及其在VIN3表达中的作用的分析.
  • 对NTL8蛋白质动态进行计算模拟和实验验证.
  • 研究温度依赖生长对蛋白质稀释的影响.

主要成果:

  • 确定了两个主导的NTL8突变,这些突变构成性地激活了VIN3表达.
  • 证明NTL8蛋白在寒冷中缓慢累积并直接调节VIN3.
  • 由于在低温下增长缓慢而导致NTL8稀释的减少是缓慢积累的关键因素.
  • 建立了温度依赖的增长是利用长期的热传感信息.

结论:

  • NTL8作为植物长期温度变化的关键热传感器.
  • 由于温度依赖的生长而导致的蛋白质稀释是季节感应的机制.
  • 这种机制为VIN3上调和冬季解释提供长期温度信息.
  • 在生物热感应中,涉及温度依赖生长的间接机制可能很普遍.