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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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对心脏性休克的暂时循环支持

Alain Combes1, Susanna Price2, Arthur S Slutsky3

  • 1Sorbonne Université, Institute of Cardiometabolism and Nutrition, Paris, France; Service de Médecine Intensive-Réanimation, Höpitaux Universitaires Pitié Salpêtrière, Assistance Publique-Höpitaux de Paris, Institut de Cardiologie, Paris, France.

Lancet (London, England)
|July 20, 2020
PubMed
概括

暂时循环支持系统为心脏性休克治疗提供了血管压缩剂和异型药物的替代方案. 这篇评论考察了它们的生理基础,证据和道德考虑.

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科学领域:

  • 心脏病学
  • 心血管医学
  • 医疗器械

背景情况:

  • 心脏性休克是由急性心脏事件或晚期心脏病引起的.
  • 目前的治疗方法如血管压缩剂和内药具有局限性,包括心肌氧需求增加和输液受损.
  • 尽管存在成本和证据差距,但机械临时循环支持系统的使用越来越多.

研究的目的:

  • 审查心脏性休克中暂时循环支持的生理基础.
  • 评估这些设备的适用性和适用性.
  • 讨论伦理问题和未来的研究需求.

主要方法:

  • 对心脏性休克的临时循环支持系统的文献综述.
  • 对生理原理和临床证据的分析.
  • 检查伦理影响和研究缺口.

主要成果:

  • 暂时的循环支持增加了心脏输出,提供了药物药物的替代品.
  • 证据支持特定的适用性和适用性仍然有限.
  • 存在重要的伦理考虑和需要高质量的研究.

结论:

  • 暂时的循环支持是一个日益复杂的心脏性休克选择.
  • 为了确定最佳使用,有效性和安全性,进一步的研究至关重要.
  • 在临床决策中,平衡利益,风险和道德问题至关重要.