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Updated: Dec 13, 2025

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
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Published on: December 23, 2020

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帕帕因类蛋白酶调节SARS-CoV-2病毒传播和天生的免疫力

Donghyuk Shin1,2,3, Rukmini Mukherjee1,2, Diana Grewe2

  • 1Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt, Germany.

Nature
|July 30, 2020
PubMed
概括

严重急性呼吸系统冠状病毒2 (SARS-CoV-2) 类似帕帕因蛋白酶 (PLpro) 分裂ISG15,阻碍抗病毒免疫力. 抑制SARS-CoV-2PLpro抑制病毒复制并增强免疫反应.

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