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lysosome-targeting 基因组用于细胞外蛋白质的降解

Steven M Banik1, Kayvon Pedram1, Simon Wisnovsky1

  • 1Department of Chemistry, Stanford University, Stanford, CA, USA.

Nature
|July 31, 2020
PubMed
概括

科学家开发了LYTACs (lysosome-targeting chimaeras) 来降解细胞外和膜蛋白. 这种新平台针对以前无法治疗的蛋白质, 提供治疗癌症和自身免疫疾病的潜力.

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