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通过降解微质中的c/EBPβ抑制神经炎症

Ada Ndoja1, Rohit Reja2, Seung-Hye Lee3

  • 1Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA.

Cell
|August 16, 2020
PubMed
概括

COP1通常抑制微质中有害的基因活动, 它的缺失导致c/EBPβ的积累,恶化神经炎症和tau病理.

关键词:
C1q 其他第一个COP没有c/EBPβ 在微质细胞神经炎症

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