儿童逆境和早期成年死亡率的发展轨迹:基于人口的队列研究
Naja H Rod1, Jessica Bengtsson1, Esben Budtz-Jørgensen2
1Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Lancet (London, England)
|August 18, 2020
概括
儿童时期的逆境,包括贫困和家庭丧失,增加了成年早期的死亡风险. 一小组多种逆境的患者面临更高的风险,突出了严重的公共卫生问题.
科学领域:
- 公共卫生
- 流行病学
- 发展心理学
背景情况:
- 童年是一个关键的发育时期,
- 童年不良经历 (ACE) 可以破坏正常发育并增加以后生活中的健康问题.
研究的目的:
- 描述不良童年经历的发展轨迹.
- 研究这些发展轨迹与成年早期死亡率之间的关联.
主要方法:
- 基于人口的队列研究,使用丹麦全国性的注册 (1980-2015).
- 包括100多万名儿童, 从出生到34岁的数据.
- 使用基于组的多轨迹聚类和生存分析 (Cox和Aalen模型).
主要成果:
- 五个不同的童年逆境轨迹被确定.
- 经历物质剥夺或损失/损失威胁的儿童的死亡风险中度增加.
- 一个小组 (3%) 经历了多种不同层面的逆境,死亡风险增加了4.54倍,其中事故,自杀和癌症是主要原因.
结论:
- 几乎一半的丹麦儿童经历了一些与成年人死亡率增加相关的逆境.
- 儿童多重逆境会显著增加成年早期的死亡风险.
- 这些发现强调了针对面临多种逆境的儿童进行公共卫生干预的必要性.
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