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Updated: Dec 11, 2025

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在活小鼠中触发的降解聚合物

Lina Cui1,2,3,4, Sandro Vivona5,6,7, Bryan Ronain Smith3

  • 1Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.

Journal of the American Chemical Society
|August 18, 2020
PubMed
概括

研究人员开发了可激活的小分子,这些分子因减少环境而在体内聚合. 这就产生了伪多糖,用于像分子成像这样的潜在生物医学应用.

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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
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