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在COVID-19中Remdesivir的有效性

Erin K McCreary1, Derek C Angus2,3

  • 1Division of Infectious Diseases, Department of Medicine, UPMC Health System and The University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

JAMA
|August 22, 2020
PubMed
概括

No abstract available in PubMed .

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The potency of a drug is the measure of its ability to produce a biological response and can be compared by looking at the half-maximum effective concentration or EC50 values of different drugs. A lower EC50 value indicates higher potency of the drug. In the dose–response curve of two antihypertensive drugs, candesartan and irbesartan, a significant difference is observed in their EC50 values. A lower EC50 value for candesartan indicates that it is more potent than irbesartan, as it...
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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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