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Updated: Dec 11, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

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产品链长度和释放模式的内在和外在编程

Chen Wang1,2, Xiaojing Wang3, Liwen Zhang1

  • 1Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing 100081, P. R. China.

Journal of the American Chemical Society
|August 25, 2020
PubMed
概括

使用真菌聚基酶 (PKS) 的组合生物合成可以产生新药化合物. 了解启动单元乙转移酶 (SAT) 和化酶 (TE) 域的作用是优化非自然产物 (uNP) 生物合成的关键.

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Protein Complexes with Interchangeable Parts

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