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Updated: Dec 9, 2025

Experimental Protocol for Detecting Mitochondrial Function in Hepatocytes Exposed to Organochlorine Pesticides
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通过减少mROS输出来缓解NASH

Qiyi Zhao1, Jiayu Liu2, Hong Deng3

  • 1Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China; Department of Infectious Diseases, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China; Guangdong Provincial Key Laboratory of Liver Disease Research, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China; Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, Guangdong 510080, China.

Cell
|September 15, 2020
PubMed
概括

在非酒精性脂肪肝炎 (NASH) 中,线粒体循环RNA SCAR (与脂肪肝相关的循环RNA ATP5B 调节剂) 的下调. 恢复SCAR可以降低线粒体ROS并缓解NASH的进展,从而成为潜在的治疗点.

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