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Updated: Dec 8, 2025

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
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一个幻觉激活的Gq-合的5-HT2A血清素受体的结构

Kuglae Kim1, Tao Che1, Ouliana Panova2

  • 1Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599-7365, USA.

Cell
|September 18, 2020
PubMed
概括

揭示了像LSD和psilocybin这样的幻觉剂如何激活5-HT2A受体 (HTR2A) 的结构性见解. 了解这些分子机制是开发神经精神疾病新疗法的关键.

关键词:
一个GPCR一个LSD迷幻药物血红素受体信号传输结构生物学

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