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Updated: May 3, 2026

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血清选择性生物结合

Julien C Vantourout1, Srinivasa Rao Adusumalli2, Kyle W Knouse1

  • 1Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|September 23, 2020
PubMed
概括

研究人员开发了一种修改蛋白质中的血清残留物的新方法. 这种方法可以将各种分子连接到胺,创建稳定的链接并扩展生物结合技术.

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Affinity chromatography is a powerful technique extensively utilized for separating and purifying specific biomolecules from complex mixtures. It capitalizes on the highly selective binding between an analyte and its counterpart, such as antibody-antigen interactions. The counterpart is immobilized on the stationary phase, forming an affinity column. The stationary phase typically consists of solid support, such as agarose or porous glass beads, immobilizing the affinity ligand. The mobile...
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