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Updated: Dec 6, 2025

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Published on: July 28, 2017

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核酸结构和功能的热可逆控制

Steve D Knutson1, Aimee A Sanford1, Colin S Swenson1

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.

Journal of the American Chemical Society
|October 5, 2020
PubMed
概括

格里奥克萨尔修饰为各种核酸提供可逆的热控制,使其在治疗和生物计算中的应用成为可能. 这种方法提高了PCR的特异性,并控制了活细胞中的基因表达.

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