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Updated: Dec 4, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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表观遗传疗法诱导逆转SINE的转录和ADAR1的依赖性

Parinaz Mehdipour1, Sajid A Marhon2, Ilias Ettayebi2,3

  • 1Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. parinaz.mehdipour@uhnresearch.ca.

Nature
|October 22, 2020
PubMed
概括

表观遗传疗法通过双链RNA (dsRNA) 激活杀死癌细胞的反元素. 将这些疗法与ADAR1抑制剂相结合,可以通过增强病毒模拟反应来加强癌症治疗.

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