皮肤黑色素瘤的危险因素. 一种实用的方法来识别有倾向的个体
A R Rhodes1, M A Weinstock, T B Fitzpatrick
1Department of Dermatology, Massachusetts General Hospital, Boston 02114.
JAMA
|December 4, 1987
概括
早期发现皮肤黑色素瘤是成功治疗的关键. 识别具有风险因素的个体,如变色和黑色素瘤病史,可以显著降低癌症死亡率.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 癌症研究 癌症研究
背景情况:
- 皮肤黑色素瘤是一个重大的公共卫生问题.
- 早期检测大大改善了治疗结果和治愈能力.
- 与许多癌症不同,黑色素瘤通常在皮肤上可见,有助于早期检测.
研究的目的:
- 为了确定皮肤黑色素瘤的关键风险因素.
- 为选择性查高风险个体的策略提供信息.
- 为了减少与黑色素瘤相关的发病率和死亡率.
主要方法:
- 对皮肤黑色素瘤的既定和新出现的风险因素的审查.
- 分析各种风险因素的相对重要性.
- 重点是临床检查,以早期检测.
主要成果:
- 关键的危险因素包括持续变化的,成年期,不规则的色素病变,先天性,高加索种族,先前的黑色素瘤,家族病史,免疫抑制,阳光敏感性和过度阳光照射.
- 这些因子按重要性排列,有助于识别面临风险的人群.
- 通过皮肤检查进行早期检测至关重要.
结论:
- 识别具有特定风险因素的个体对于有针对性的查至关重要.
- 积极查和及时治疗黑色素瘤可以降低死亡率.
- 公众对黑色素瘤风险因素的认识可以赋予个人和医疗保健提供者权力.
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