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Updated: Jul 28, 2026

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预测蛋白质电荷工程的静电效应

M J Sternberg1, F R Hayes, A J Russell

  • 1Department of Crystallography, Birkbeck College, London, UK.

Nature
|November 5, 1987
PubMed
概括

预测蛋白质的静电效应是蛋白质设计的关键. 一个计算模型准确地预测了pKa在细素中的变化,有助于理解催化活性和指导蛋白质工程工作.

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