在轨道前皮层编码的值与经济选择有因果关系
Sébastien Ballesta1,2,3, Weikang Shi1, Katherine E Conen1,4
1Department of Neuroscience, Washington University in St Louis, St Louis, MO, USA.
Nature
|November 3, 2020
概括
科学家们用子的电刺激来证明,大脑在轨道前皮层 (OFC) 的活动通过改变主观价值计算来对经济选择产生因果影响.
科学领域:
- 神经科学
- 神经经济学
- 决策科学
背景情况:
- 经济选择在历史上与主观价值计算有关 (伯诺利,史密斯,本瑟姆).
- 在决策过程中,神经元编码主观价值.
- 之前的证据将大脑活动与经济选择联系在一起.
研究的目的:
- 确定神经元活动与经济选择之间的因果关系.
- 研究OFC在主观值计算和比较中的作用.
主要方法:
- 这两项实验涉及OFC在 rhesus子中的电刺激.
- 通过低电流和高电流刺激来操纵神经元活动.
- 观察对主观价值观和随后的选择的影响.
主要成果:
- 通过增加主观价值,
- 高电流刺激扰乱了主观价值计算和比较,增加了选择的可变性.
- 证明OFC活动与经济决策之间存在因果关系.
结论:
- 在OFC中神经元活动与经济选择有因果关系.
- 在经济决策的评估和选择过程中,OFC发挥着至关重要的作用.
- 提供了经济行为主观价值的神经基础的直接证据.
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