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Updated: Dec 2, 2025

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全基因组的CRISPR屏幕揭示了SARS-CoV-2感染的关键宿主因素

Jin Wei1, Mia Madel Alfajaro1, Peter C DeWeirdt2

  • 1Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT 06520, USA; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.

Cell
|November 4, 2020
PubMed
概括

研究人员使用CRISPR屏幕识别了SARS-CoV-2感染的关键宿主基因. 这些发现揭示了冠状病毒的新治疗点和关键途径,包括HMGB1和SWI/SNF复合体.

关键词:
美国在CRISPR屏幕上表观遗传学一个 HMGB其他病例中东呼吸系统综合征冠状病毒SWI/SNF复合体严重急性呼吸系统综合征

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