改变形状的纳米材料:表面不对称性使得原管和板的pH依赖形成和相互转换
Andrea D Merg1, Gavin Touponse1, Eric van Genderen2
1Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.
Journal of the American Chemical Society
|November 10, 2020
概括
研究人员用仿 (CMP) 来制造动态生物材料, 这些结构可以在形式之间转换,为响应性合成材料提供新的可能性.
科学领域:
- 生物材料科学
- 超分子化学
- 纳米技术
背景情况:
- 动态的可转化生物材料对于合成材料的发展至关重要.
- 原仿真 (CMP) 为生物材料设计提供了一个多功能平台.
- 控制自我组装成特定的形态仍然是一个挑战.
研究的目的:
- 从异构CMP对设计和合成晶体超分子结构.
- 研究自发组装到1D管或2D纳米板.
- 建立动态响应的1D和2D组件的指导方针.
主要方法:
- 使用充电补充CMP对进行自组装.
- 使用传输电子显微镜 (TEM),原子力显微镜 (AFM) 和冷电子显微镜 (cryo-EM) 来进行结构特征.
- 应用小角X射线散射 (SAXS) 和广角X射线散射 (WAXS) 进行格子结构分析.
主要成果:
- 自组装成1D超多孔管 (>100 nm孔径) 或2D双层纳米片的CMP对.
- 发现了一种新的结晶原管形态.
- 证明了管道是由二维原三环层的自动滚动产生的.
- 通过pH操纵和CMP序列调整显示了板和管形态之间的相互转换.
结论:
- 为构建具有动态响应的1D和2D生物材料组件制定了指导方针.
- 在基于CMP的材料中证明了结构编程的形态转换.
- 推进模仿自然材料的合成材料的开发.
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