急性软骨炎:原因,诊断和治疗方法
Olwen C Murphy1, Kevin Messacar2, Leslie Benson3
1Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Lancet (London, England)
|December 28, 2020
概括
急性软骨炎 (AFM) 是由肠道病毒引起的残疾性脊髓灰质炎类疾病. 这一审查指导了AFM的诊断,管理和康复,这是一个重要的公共卫生问题.
科学领域:
- 神经学
- 传染性疾病
- 公共卫生
背景情况:
- 急性软骨髓炎 (AFM) 是一种主要影响儿童的严重神经疾病.
- 肌肉突然变弱, 导致呼吸衰竭, 模仿其他神经疾病.
- 自2012年以来的疫情表明非脊髓灰质炎肠道病毒是病因,
研究的目的:
- 审查急性软骨炎的流行病学,临床特征和结果.
- 为AFM患者的诊断,治疗和康复提供指导.
- 确定未来的研究方向,以了解和治疗AFM.
主要方法:
- 对急性松肌炎的现有文献的审查.
- 诊断临床表现,神经成像和脑脊液特征的分析.
- 检查患者的结果和康复需求.
主要成果:
- AFM表现为严重的肌肉衰弱,通常具有显著的残留残疾.
- 诊断需要临床,成像和脑脊液的结合,因为没有单一的测试是最终的.
- 患者需要专业的长期康复治疗.
结论:
- 机械空气管理是一个重大的公共卫生挑战,需要改进诊断和管理策略.
- 对宿主-病原体相互作用和向治疗的进一步研究至关重要.
- 了解遗传,病毒和免疫因素将改善患者的长期结果.
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