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抑制剂可以杀死阴性细菌并激活免疫清除

Kumar Sachin Singh1, Rishabh Sharma1, Poli Adi Narayana Reddy2

  • 1Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, USA.

Nature
|December 28, 2020
PubMed
概括

新的IspH抑制剂通过向甲基红酸盐路径来杀死多药耐药细菌. 这些前药也激活人体Vγ9Vδ2T细胞,提供了一种对抗细菌感染和限制耐药性的双重方法.

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