作为生物食品质量控制系统的食物过敏
Esther B Florsheim1, Zuri A Sullivan1, William Khoury-Hanold1
1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Cell
|January 15, 2021
概括
我们的免疫系统,特别是过敏免疫系统, 作为食物质量的传感器. 但过度反应可能会导致食物过敏.
科学领域:
- 免疫学
- 感官生物学
- 食品科学
背景情况:
- 食物提供营养, 但也提供毒素和病原体.
- 嗅觉,味觉和肠道化学感觉等感官系统是为了监测食物质量而进化而来的.
- 过敏免疫在食品质量控制中的作用被低估了.
研究的目的:
- 提出过敏免疫作为一种食品质量控制机制.
- 探索过敏防御如何向与有害物质相关的食物抗原.
- 了解过度过敏防御与病态食物过敏之间的联系.
主要方法:
- 关于感官系统和过敏免疫力的现有文献的审查.
- 将过敏反应纳入食品质量评估的假设框架.
- 对免疫反应在食品安全中的进化作用的分析.
主要成果:
- 过敏免疫能增加对与毒素相关的食物抗原的防御能力.
- 这种免疫反应作为一种额外的食品质量控制层.
- 这些防御系统的失调会导致食物过敏的发展.
结论:
- 过敏免疫系统在保护我们免受有害食物成分的影响方面起着至关重要的作用, 但常常被忽视.
- 了解这种功能对于解读食物过敏的起源至关重要.
- 这种观点将过敏免疫作为我们与食物互动的组成部分.
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