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前庭检查的研究重点:国家心脏,肺和血液研究所虚拟研讨会的报告

Emelia J Benjamin ^1,2, Alan S Go ^3,4,5, Patrice Desvigne-Nickens ⁶

¹Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, MA (E.J.B.).
²Department of Epidemiology, Boston University School of Public Health, MA (E.J.B.).
³Division of Research, Kaiser Permanente Northern California, Oakland (A.S.G.).
⁴Departments of Epidemiology, Biostatistics, and Medicine, University of California, San Francisco (A.S.G.).
⁵Departments of Medicine, Health Research, and Policy (A.S.G.), Stanford University, CA.
⁶Division of Cardiovascular Sciences (P.D.-N., L.S.C.), National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
⁷Department of Neurology, Center for Genomic Medicine, and McCance Center for Brain Health, Massachusetts General Hospital, Boston (C.D.A.).
⁸Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, UK (B.C.).
⁹Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis (L.Y.C.).
¹⁰Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, the Netherlands (H.J.G.M.C.).
¹¹Heart Research Institute, Charles Perkins Centre, and Concord Hospital Department of Cardiology, Concord Clinical School, University of Sydney, Australia (B.F.).
¹²StopAfib.org, American Foundation for Women's Health, Decatur, TX (M.T.H.).
¹³Population Health Research Institute, McMaster University, Hamilton, ON, Canada (J.S.H.).
¹⁴Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medicine, New York, NY (H.K.).
¹⁵Office of Biostatistics Research (D.-Y.K.), National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
¹⁶Department of Medicine, Division of Cardiology, UT Southwestern Medical Center, Dallas, TX (M.S.L.).
¹⁷Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC (R.D.L., J.P.P., S.M.A.-K.).
¹⁸Cardiovascular Research Center and Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston (S.A.L.).
¹⁹Department of Medicine, Division of Cardiology, University of Massachusetts Medical School, Worcester (D.D.M.).
²⁰Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (P.A.N.).
²¹Department of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany (R.B.S.).
²²DZHK (German Center for Cardiovascular Research), partner site Hamburg/Kiel/Luebeck, Germany (R.B.S.).
²³Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, (D.E.S.).
²⁴Department of Cardiology, University of Groningen, University Medical Center Groningen, the Netherlands (I.C.V.G., R.G.T.).
²⁵Department of Cardiology, Martini Hospital, Groningen, the Netherlands (R.G.T.).
²⁶Center for Digital Health (M.P.T.), Stanford University, CA.
²⁷Veterans Affairs Palo Alto Health Care System, CA (M.P.T.).

⁰Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, MA (E.J.B.).

Circulation +

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2021年一月25日

在PubMed上查看摘要

概括

早期发现心房是预防中风等严重并发症的关键. 本报告概述了有效的AF查策略的研究重点,并了解早期检测的影响.

科学领域

心脏病学
公共卫生
医学研究

背景情况

临床上确定的心房动会增加严重并发症的风险,包括中风,心力衰竭和死亡.
在出现并发症之前, 人们往往无法发现肌肉炎, 这凸显了早期发现策略的必要性.
关于最佳查方法和检测未诊断的AF的影响存在不确定性.

研究的目的

总结国家心脏,肺和血液研究所 (NHLBI) 虚拟研讨会确定的心房动查的主要研究重点.
解决关于检测未诊断的AF最有效策略的知识差距.
旨在改善未诊断的关节炎患者的诊断和治疗的研究.

主要方法

一个虚拟研讨会召集了全球专家来审查当前的知识,并确定AF查中的关键研究缺口.
讨论重点包括机会性查,AF作为风险因素/标志物,AF负担,试验设计和中风后查.
该研讨会旨在确定创新,资源效率和临床相关的AF查研究的优先事项.

主要成果

在五个主要领域确定了关键的研究重点.
报告强调需要澄清机会性查的作用和AF作为风险因素或标志物的地位.
优先考虑的内容包括了解AF负担与结果之间的关系,设计有效的随机试验,并评估中风后的查.

结论

进一步的研究是建立最佳查和管理未诊断的心房动的关键.
优先研究已确定的领域将有助于诊断,治疗和预后.
需要创新和多样化的研究方法来改善未被诊断的肌肉功能障碍患者的治疗结果.

关键词:

心房动诊断查计划预防和控制进行研究一次中风