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Updated: Jul 14, 2026

Identification of Kinase-substrate Pairs Using High Throughput Screening
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蛋白激酶C的主要基质的刺激依赖的基化

A A Aderem1, K A Albert, M M Keum

  • 1Rockefeller University, New York, New York 10021.

Nature
|March 24, 1988
PubMed
概括

细菌脂多糖 (LPS) 通过化蛋白酶C (PKC) 基质,触发巨细胞的反应. 这种myristoylation可能会将蛋白质向细胞膜,调解LPS诱导的细胞信号传递.

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