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Updated: Nov 17, 2025

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过度的O-化会导致心脏衰竭和突然死亡

Priya Umapathi1,2, Olurotimi O Mesubi1,2, Partha S Banerjee3

  • 1Division of Cardiology (P.U., O.O.M., N.A., Q.W., E.D.L., Y.W., J.M.G., O.E.R.G., M.E.A.), The Johns Hopkins University School of Medicine, Baltimore, MD.

Circulation
|February 17, 2021
PubMed
概括

过度的O-GlcNAcylation通过损害线粒体能量导致心力衰竭. 减弱O-GlcNAcylation对心脏重塑有益,并可能为心肌病提供一种新的治疗策略.

关键词:
没有.尿素二酸N-乙糖胺心脏节律失常心脏衰竭高血压过度增长翻译后的蛋白质加工

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