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活体CRISPR查揭示了支持CD8+T细胞命运的营养信号传递过程

Hongling Huang1, Peipei Zhou1, Jun Wei1

  • 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell
|February 26, 2021
PubMed
概括

像Slc7a1和Slc38a2这样的营养载体调节记忆T细胞 (TMEM) 的分化. Pofut1将营养信号与T细胞命运联系在一起,影响T细胞效应 (TEFF) 和TMEM发育.

关键词:
国内生产总值-糖没有T细胞记忆细胞周期的结束免疫新陈代谢在体内聚合的CRISPR查代谢异质性营养信号系统免疫学终端效应器单元

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