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Isolation of Murine Lymph Node Stromal Cells
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淋巴结中的单细胞衍生S1P调节免疫反应

Audrey Baeyens1, Sabrina Bracero1,2, Venkata S Chaluvadi1,3

  • 1Skirball Institute of Biomolecular Medicine, New York University Langone Medical Center, New York, NY, USA.

Nature
|March 4, 2021
PubMed
概括

在免疫反应期间,由炎症单细胞驱动的sphingosine 1- phosphate (S1P) 水平在淋巴结中升高. 这种增加会延长T细胞的存在,从而加剧自身免疫性疾病的严重程度.

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