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如何制造更好的T细胞:体内CRISPR查有答案

Matteo Villa1, Michal A Stanczak1, Erika L Pearce2

  • 1Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.

Cell
|March 5, 2021
PubMed
概括

研究人员使用体内CRISPR查发现了控制CD8+T细胞免疫力的新方法. 这一发现旨在通过增强T细胞反应来改善癌症和感染的治疗方法.

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CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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