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从COVID-19中吸取的紧急教训:为什么世界需要一个稳定的,协调的系统和全球研发的可持续融资
Nicole Lurie1, Gerald T Keusch2, Victor J Dzau3
1Coalition for Epidemic Preparedness Innovations, Oslo, Norway; Harvard Medical School, Boston, MA, USA.
Lancet (London, England)
|March 12, 2021
概括
研究和开发生态系统已经改善了疫情准备,由快速的COVID-19疫苗和治疗开发证明. 然而,全球融资和其他关键领域需要加强真正有效的应对系统.
科学领域:
- 传染病研究和开发
- 全球卫生安全
- 生物制药创新
背景情况:
- 研究和开发 (R&D) 生态系统已经适应包括流行传染病,最近爆发的疫情.
- 随着COVID-19大流行,疫苗和治疗方法的开发加速,新型临床试验以及快速制造和授权取得了成功.
研究的目的:
- 确定疫情防控和应对的研发生态系统中的缺口.
- 提出提高研发过程效率和速度的优先事项.
- 强调在持续的全球卫生危机中迫切需要解决这些差距.
主要方法:
- 分析过去十年研发生态系统的演变.
- 在COVID-19疫情期间评估研发成果.
- 确定需要改进的关键领域,包括全球融资和促进科学.
主要成果:
- 在COVID-19期间一年内迅速开发和部署医疗对策表明了研发方面的重大进展.
- 在建立完全高效和有效的端到端研发准备和应对系统方面存在持续的差距.
- 需要加强的关键领域包括全球融资机制,支持科学和产品开发过程.
结论:
- 虽然取得了进展,但真正强大的疫情应对研发生态系统需要进一步发展.
- 解决关键缺口,特别是全球融资,对于未来的疫情准备至关重要.
- 需要采取紧急和协调的行动, 加强研发基础设施, 应对疫情对健康,社会和经济造成的破坏性影响.
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