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Updated: Nov 12, 2025

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在黑色素瘤中鉴定细菌衍生的HLA结合

Shelly Kalaora1, Adi Nagler1, Deborah Nejman1

  • 1Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

Nature
|March 18, 2021
PubMed
概括

人体瘤中的细胞内细菌通过人白细胞抗原 (HLA) 分子呈现,可能影响癌症免疫力和治疗反应. 这项研究揭示了瘤细胞所呈现的细菌抗原,

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相关概念视频

Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
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