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Updated: Nov 12, 2025

Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae
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Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae

Published on: September 11, 2022

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通过DNA驱动的凝结组装了介质DNA断裂机制

Corentin Claeys Bouuaert1,2, Stephen Pu3, Juncheng Wang4

  • 1Molecular Biology Program, Memorial Sloan Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, USA. corentin.claeys@uclouvain.be.

Nature
|March 18, 2021
PubMed
概括

分离过程中染色体的准确分离取决于Spo11产生的DNA双链断裂 (DSB). 该研究揭示了Rec114,Mei4和Mer2蛋白如何自组成功能,控制DSB的形成以保持基因组的稳定性.

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