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Updated: Nov 12, 2025

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在克隆性血液形成中,AIM2炎症酶会加剧动脉样硬化

Trevor P Fidler1, Chenyi Xue2,3, Mustafa Yalcinkaya4

  • 1Division of Molecular Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. tpf2103@cumc.columbia.edu.

Nature
|March 18, 2021
PubMed
概括

由JAK2V617F等突变驱动的克隆性血液形成,通过增加巨细胞的增殖和炎症酶激活来加速动脉样硬化. 针对炎症体或白蛋白-1β可能会降低心血管风险.

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