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Updated: Nov 12, 2025

Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains
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Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains

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细胞表面工程使用DNA酶:金属离子介导控制细胞与细胞的相互作用

Ruo-Can Qian1, Ze-Rui Zhou1, Weijie Guo

  • 1Key Laboratory for Advanced Materials, Feringa Nobel Prize Scientist Joint Research Center, Joint International Laboratory for Precision Chemistry, Frontiers Science Center for Materiobiology & Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, P. R. China.

Journal of the American Chemical Society
|March 22, 2021
PubMed
概括

研究人员开发了一种基于DNA酶的新方法,用于使用金属离子控制细胞相互作用. 这一突破使精确的细胞组装和拆卸成为可能,进步了细胞命运控制和治疗应用.

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Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials

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相关概念视频

Cell-surface Signaling01:21

Cell-surface Signaling

Hormones—or any molecule that binds to a receptor, known as a ligand—that are lipid-insoluble (water-soluble) are not able to diffuse across the cell membrane. In order to be able to affect a cell without entering it, these hormones bind to receptors on the cell membrane. When a first messenger, a hormone, binds to a receptor, a signal cascade is set off, causing second messengers, proteins inside the cell, to become activated, resulting in downstream effects.
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