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Updated: Nov 10, 2025

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对核心发起者的预启动复合组合的结构洞察

Xizi Chen1, Yilun Qi1, Zihan Wu1

  • 1Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering and Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College of Fudan University, Shanghai 200032, China.

Science (New York, N.Y.)
|April 2, 2021
PubMed
概括

转录因子IID (TFIID) 结构揭示了真核转录中预启动复合体 (PIC) 组合的两个不同的途径. 这些通路汇聚到一个共同的全PIC,稳定RNA聚合酶II并促进其激活.

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