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Updated: Nov 9, 2025

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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Published on: June 15, 2017

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CRL4AMBRA1是D型环素的主要调节剂

Daniele Simoneschi1,2, Gergely Rona1,2,3, Nan Zhou4

  • 1Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.

Nature
|April 15, 2021
PubMed
概括

研究人员确定CRL4AMBRA1是向D型环的泛素结合酶. 失去AMBRA1会导致循环蛋白积累和发育缺陷,突出AMBRA1

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