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Updated: Nov 9, 2025

Generation of Genome-wide Chromatin Conformation Capture Libraries from Tightly Staged Early Drosophila Embryos
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在早期的Drosophila胚胎中,HP1驱动着新的3D基因组重组

Fides Zenk1,2, Yinxiu Zhan3,4, Pavel Kos3

  • 1Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.

Nature
|April 15, 2021
PubMed
概括

在早期的Drosophila胚胎中建立3D基因组组织至关重要. HP1a驱动了周心聚类,染色体折叠和B区形成,揭示了它在基因组结构的表观遗传调节中的作用.

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Polytene Chromosomes02:04

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Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also...
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