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Updated: Nov 7, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

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eNOS基因的流量响应性Cis-DNA元素的活体功能:基于染色体的机制的作用

Kyung Ha Ku1,2, Michelle K Dubinsky3,2, Aravin N Sukumar3,2

  • 1Department of Laboratory Medicine and Pathobiology (K.H.K., M.Y.M.F., R.N., E.T., B.J.K., P.A.M.).

Circulation
|April 29, 2021
PubMed
概括

剪切应激反应元件 (SSRE) 和KLF元件对于动脉内皮氧化合成酶 (eNOS) 基因表达至关重要. 流量依赖的DNA甲基化在体内调节eNOS,为动脉样硬化的发展提供了洞察力.

关键词:
动脉样硬化内皮细胞表观遗传学血液动力学氧化合成酶III型

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