爱琴海宫殿文明的基因组历史
Florian Clemente1, Martina Unterländer2, Olga Dolgova3
1Department of Computational Biology, University of Lausanne, 1015 Lausanne, Switzerland; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Cell
|April 30, 2021
概括
早期希腊青铜时代 (BA) 的人口显示出新石器时代的爱琴海人同质血统,迁徙有限. 后来的中期BA种群包含了与草原相关的重要祖先,形成了现代希腊基因组.
科学领域:
- 古代基因组学
- 古遗传学
- 欧洲史前史
背景情况:
- 希腊青铜时代 (BA) 涵盖了冰岛,米诺和赫拉迪文化.
- 这个时代被城市化,复杂的社会,专门的工艺,农业和早期的文字系统所定义.
研究的目的:
- 调查早期到中期青铜时代的爱琴海人口的遗传景观.
- 了解这一形成时期的人口动态和迁移模式.
主要方法:
- 从早期到中青铜时代的6个人的全基因组测序.
- 11个人的线粒体基因组测序.
- 对古代DNA进行分析以推断祖先和人口关系.
主要成果:
- 早期青铜时代 (EBA) 的爱琴海基因组是基因同质的,主要来自新石器时代的爱琴海人.
- EBA 种群显示出来自东方的有限基因流动,这可以通过在亚纳托利亚人中发现的与高加索有关的祖先来证明.
- 来自希腊北部的中青铜时代 (MBA) 个人表现出相当大的 (~50%) 庞特-里海草原相关的祖先,可追溯到大约公元前2600-2000年.
结论:
- 在爱琴海,从新石器时代到青铜时代的过渡并非由大规模的人口替代驱动,而是由连续性和有限的外部基因流动驱动的.
- 在中青铜时代,庞特-里海草原的大量迁移在塑造希腊人口的基因构成方面发挥了关键作用.
- 这些青铜时代的基因流动事件有助于现代希腊人的遗传特征.
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