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Updated: Nov 7, 2025

LERLIC-MS/MS for In-depth Characterization and Quantification of Glutamine and Asparagine Deamidation in Shotgun Proteomics
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在蛋白质组中的化部位生成的脱氨基酸中添加LanCL

Kuan-Yu Lai1, Sébastien R G Galan2, Yibo Zeng3

  • 1Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

Cell
|May 1, 2021
PubMed
概括

由排泄反应造成的蛋白质损伤由LanCL酶修复,这些酶将谷添加到脱氨酸/脱丁氨酸中. 这种C- 氨基化使异常激酶失活,对生理功能至关重要,防止过早死亡.

关键词:
C-谷氨基化美国其他国家脱水氨酸脱水氨酸酸兰西通过酸酶蛋白质损伤

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