在舌头达到或错过目标时依赖于皮层的纠正
Tejapratap Bollu1, Brendan S Ito1, Samuel C Whitehead1
1Department of Neurobiology and Behavior, Cornell University, Ithaca, NY, USA.
Nature
|May 20, 2021
概括
研究人员发现了大脑如何控制饮酒时舌头的快速移动. 通过使用先进的成像和人工智能, 他们发现大脑会快速纠正,
科学领域:
- 神经科学
- 发动机控制
- 生物力学
背景情况:
- 精确的舌头控制对于吃饭,饮酒和发音等基本功能至关重要.
- 了解控制快速复杂的舌头运动的神经机制或语言动力学, 由于它们的速度和测量难度,
研究的目的:
- 研究小鼠时3D舌头运动的神经控制.
- 阐明前侧运动皮质在语言任务中的在线运动校正中的作用.
主要方法:
- 使用千赫兹率成像来捕捉高速的3D舌头运动.
- 使用基于深度学习的神经网络来分析和重建语言动态.
- 用光抑制来选择性地破坏前侧运动皮层中的神经活动.
主要成果:
- 识别了时的纠正次移动,类似于灵长类达到任务时观察到的在线纠正.
- 证明前侧运动皮质的光抑制导致纠错和低度,导致失误.
- 发现前侧运动皮层中的神经活动编码了有关校正次运动和预测喷口接触的错误的信息.
结论:
- 尽管鼠标的时间很短, 但它具有复杂的在线运动控制机制, 类似于灵长类的.
- 在时,前侧运动皮层起到关键作用,
- 这项研究为复杂生物系统中快速适应性运动的神经基础提供了新的见解.
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