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José Danglad-Flores1, Sabrina Leichnitz1,2, Eric T Sletten1

  • 1Department of Biomolecular Systems, Max-Planck-Institute of Colloids and Interfaces, 14476 Potsdam, Germany.

Journal of the American Chemical Society
|June 1, 2021
PubMed
概括

一种用于碳水化合物合成的新型自动化合成器为复杂的甘氨酸组装提供了精确的温度控制. 这项创新加速了生物医学研究的分支,硫酸和无保护甘氨酸的制造.

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Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
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