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Updated: Jun 14, 2026

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设计一个蓝光可诱导的SpyTag系统 (BLISS)

Emily J Hartzell1, Justin Terr1, Wilfred Chen1

  • 1Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, United States.

Journal of the American Chemical Society
|June 2, 2021
PubMed
概括

研究人员使用SpyTag和光氧电压域2 (AsLOV2) 开发了一种蓝光诱导蛋白结合系统 (BLISS). 这种系统可以对蛋白质反应进行精确的空间和时间控制,增强生物制造和光遗传学.

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相关概念视频

Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.