在复发性多发性骨髓瘤 (IKEMA) 中使用伊萨图西玛,卡菲尔佐米布和德克萨米松:多中心,开放性,随机的第三阶段试验

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...