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Updated: Oct 29, 2025

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
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在唐氏综合征中绘制白血病的细胞起源和早期演变

Elvin Wagenblast1, Joana Araújo2,3,4,5,6, Olga I Gan2

  • 1Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada. elvin.wagenblast@uhnresearch.ca john.dick@uhnresearch.ca eric.lechman@uhnresearch.ca.

Science (New York, N.Y.)
|July 10, 2021
PubMed
概括

患有唐氏综合征的儿童患髓性白血病的风险更高. 基因编辑揭示了GATA1突变引发了三发性细胞的白血病前期,但白血病的进展涉及凝聚素基因突变,并且独立于三发性细胞.

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