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对Prp5如何校对前mRNA分支部位的结构洞察

Zhenwei Zhang1, Norbert Rigo2, Olexandr Dybkov2

  • 1Department of Structural Dynamics, MPI for Biophysical Chemistry, Göttingen, Germany.

Nature
|August 5, 2021
PubMed
概括

这项研究揭示了Prp5是如何通过间接校对分支部位来确保准确的mRNA前拼接. 在Hsh155蛋白重塑之前, 它会阻止组装, 确保保真性.

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