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Updated: Oct 24, 2025

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在人体SLE中,红状腺线粒体保留会触发神经依性I型干扰素

Simone Caielli1, Jacob Cardenas2, Adriana Almeida de Jesus3

  • 1Drukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.

Cell
|August 13, 2021
PubMed
概括

红细胞中的线粒体去除缺陷与全身性红斑狼 (SLE) 病变有关. 在SLE患者中含有线粒体的红细胞的积累与疾病活性和I型干扰素的产生有关.

关键词:
CANDLE综合症其他类型自体免疫性cGAS 公司人体红色形成干扰素线粒体DNA细胞分裂蛋白质组系统性红斑狼

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