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Updated: Oct 22, 2025

Author Spotlight: Establishing CENP-E Knockout HeLa Cells – A Novel Approach to Study Kinesin-7 CENP-E Biology and its Inhibitors
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编辑RNA限制了过度活跃的毛激酶

Dongdong Li1,2,3,4, Yufan Liu1,2,3,4, Peishan Yi1,2,3,4

  • 1Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, China.

Science (New York, N.Y.)
|August 27, 2021
PubMed
概括

细胞通过RNA编辑来调节高活性蛋白激酶. 在ADR-2中发生的突变,一种RNA腺酶,拯救了由过度活跃的激酶引起的状细胞缺陷,揭示了一个新的反机制.

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