患有COVID-19的医院幸存者的1年结果:纵向队列研究
Lixue Huang1, Qun Yao2, Xiaoying Gu3
1Department of Pulmonary and Critical Care Medicine, Capital Medical University, Beijing, China; Department of Pulmonary and Critical Care Medicine, National Center for Respiratory Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China.
Lancet (London, England)
|August 29, 2021
概括
大多数COVID-19幸存者在身体上恢复良好,并在一年内恢复工作. 然而,呼吸不良和焦虑等长期COVID-19症状仍然存在,女性出现更严重的后果.
科学领域:
- 医学研究
- 传染性疾病
- 肺病学
背景情况:
- 医院出院后COVID-19对健康的长期影响尚不完全理解.
- 这项研究旨在比较COVID-19幸存者的症状出现后6个月和12个月的健康后果.
研究的目的:
- 综合评估和比较6个月和12个月后COVID-19医院幸存者的身体,功能和心理健康结果.
- 确定COVID-19幸存者的持续症状和降低生活质量的危险因素.
主要方法:
- 一项涉及1276名从武汉医院出院的COVID-19幸存者的双向队列研究.
- 随访包括关于症状和生活质量的问卷,体检,功能测试 (6分钟步行测试) 和实验室评估.
- 与12个月后匹配的非COVID-19对照进行比较.
主要成果:
- 幸存者中至少有一个后续症状的比例从6个月的68%降至12个月的49%.
- 在6至12个月期间,呼吸不良和焦虑/抑郁率略有增加.
- 与男性相比,女性的疲劳,焦虑/抑郁和扩散障碍的几率更高.
结论:
- COVID-19 幸存者在一年内身体和功能状况明显恢复,大多数人恢复工作.
- 尽管整体情况有所改善,但显著比例的患者出现持续症状,他们的健康状况仍低于一般人群.
- 呼吸障碍和心理健康问题等特定症状需要继续监测和支持COVID-19幸存者.
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