对心房系统查 (STROKESTOP) 的临床结果:多中心,并行组,无遮掩,随机对照试验
Emma Svennberg1, Leif Friberg2, Viveka Frykman2
1Karolinska Institutet, Department of Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Lancet (London, England)
|September 1, 2021
概括
针对老年人进行心房动的系统查显示了小的净益,减少了中风和死亡. 这种方法在老年人群中是安全有效的早期检测和治疗.
科学领域:
- 心脏病学
- 老年病学
- 公共卫生
背景情况:
- 心房动是缺血性中风的主要危险因素.
- 早期检测和抗凝剂治疗可以显著降低中风风险和死亡率.
- 本研究研究了老年人群中系统性心房动查的影响.
研究的目的:
- 在75-76岁的个体中,评估是否有系统地查心房动会降低死亡率和发病率,而不是没有查.
- 通过查计划评估早期动检测的安全性和有效性.
主要方法:
- 一个多中心,随机对照试验 (STROKESTOP) 涉及75-76岁的瑞典人.
- 参与者被随机分配到心房的查组或对照组.
- 查包括14天心电图 (ECG) 检测时提供口服抗凝剂.
主要成果:
- 超过28000人被随机选择;7165人参加了查 (51.3%).
- 随访时间中位数为6. 9年后,查组的初级终点事件 (中风,栓塞,出血,死亡) 比对照组少 (HR为0. 96, p=0. 045).
- 查干预显示了统计学上显著的,尽管很小,净收益.
结论:
- 在老年人群中对心房的系统查提供了很小的净益.
- 这些发现表明,对老年人进行心房动查是一种安全且有益的策略.
- 通过查及早发现和治疗心房动,可有助于减少心血管不良后果.
相关概念视频
Assessment of blood pressure in brachial artery(one-step method)
1.4K
This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Prepare for the Procedure:
1.4K
Assessment of blood pressure in brachial artery(two-step method)
2.1K
Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
2.1K
Pre-Procedural Guidelines for Assessing Blood Pressure
882
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
882
Regulation of Stroke Volume
7.4K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
7.4K
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
4.7K
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
4.7K
Acute Coronary Syndrome III: Diagnostic Studies
500
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
500


